Urinalysis can be used as part of an investigation of recurrent colic, stranguria, dysuria, polyuria, polydypsia weight loss and other presenting complaints.

When catheterised urine samples are obtained, consideration of the effects of sedation is important. alpha-2 agonist sedatives (detomidine, xylazine, romifidine) have both acute diuretic and hyperglycaemic effects. The diuretic effect is unlikely to alter the properties of the subsequently collected urine sample as a few mLs of most recently produced diuresed urine should not significantly affect the previously accumulated urine in the bladder. However, even a small amount of glycosuria might confuse diagnostic interpretation. Hence acepromazine (5-10 mg/100kg iv) perhaps supplemented by a nose twitch or a small dose of detomidine (0.5 mg/100 kg iv) should be used as necessary in geldings. In mares the use of stocks or a stable door may avoid the need for sedation.

Urinalysis and the investigation of polydipsia and polyuria

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For many years our practice have used the LEH lab for our clinical pathology work. Andy and the rest of his team offer an amazingly efficient, thorough and friendly service. The advice and support they provide is on an individual case by case basis and has proved invaluable many times. This close working relationship makes them feel like the ‘extremely knowledgable’ colleague within the practice! — Alistair Field MRCVS, Clent Hills Veterinary Group, Worcs.